Discover Our World
Cells do not act in isolation!
They communicate, cooperate, and sometimes interfere with one another.
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Here, at the Genoa ImmunoPathology Center (GIPC), we study how immune cells and other cell populations are organized and interact within tissue, combining morphology with multiplex immunohistochemistry, digital pathology, and molecular profiling.
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The GIPC is a pathology research institute based at the Department of Surgical Sciences and Integrated Diagnostics, University of Genoa. Our work focuses on gastrointestinal, hepatobiliary and transplant pathology across neoplastic and non-neoplastic disease.
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Our Research Approach
Tissue-tethered Immunopathology
We examine cellular phenotypes, spatial relationships, and tissue compartments to generate and test hypotheses about disease mechanisms and potential therapeutic targets.
We use image-based methods to transform tissue architecture into measurable, analyzable data while preserving its morphological and spatial context.
Quality and Reproducibility
We prioritize fit-for-purpose methods, appropriate controls, transparent analyses, and cautious interpretation of exploratory findings. This is particularly important when evaluating prognostic and predictive biomarkers that may inform clinical decision-making and patient management.
Green Pathology
We investigate practical ways to reduce the environmental footprint of diagnostic and research pathology without compromising scientific quality, diagnostic accuracy or safety.